地氯雷他定Desloratadine
powder, ≥98% (HPLC)
Synonym: Clarinex?, 8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H- benzo[5,6]cyclohepta[1,2,b]pyridine
CAS Number: 100643-71-8
Linear Formula: C19H19ClN2
Molecular Weight: 310.82
Description
Biochem/physiol Actions Desloratadine is a selective and nonsedating histamine H1 receptor antagonist, an active metabolite of loratadine (Claritin), used to relieve hay fever and allergy symptoms with less drowsiness than other antihistamines; does not significantly inhibits cardiac K+ channels at clinically achievable blood levels. Free from antimuscarinic/anticholinergic effects.
Legal Information Clarinex is a registered trademark of Schering Corp.
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